1. Was the design used appropriate to the research questions?2. Was there anything about the way that participants were chosen or their characteristics that could have influenced the findings?3. Were important extraneous variables and bias controlled? If yes, how?4. Was there anything about how the study was conducted that could have influenced the findings?5. If an intervention was tested, answer the following five questions? (For Random Controlled Tests).a. How were participants assigned to groups and were groups similar at the start (before the intervention)?b. Were the interventions well defined and consistently delivered (fidelity to treatment)?c. Were study groups treated equally other than the difference in the intervention?d. If no difference was found (results of the study), was the sample size large enough to find a difference, if one existed?e. If a difference was found, are you confident it was due to differences caused by the intervention?6. For each main finding, is it credible (valid)?7. Is each finding consistent with or different from previous findings in this area of study (For non-RCT studies)Clinical Significance8. Is the frequency, association, or treatment effect impressive enough to be confident that the findings would make a clinical difference if used as the basis for care delivery?9. Are study findings clinically significant?
