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Why does fear motivate humanity to continue to make the wrong choices? Is there such a thing as wrong choices when every choice is part of the experience?

Remembering that I’ll be dead soon is the most important tool I’ve ever encountered to help me make the big choices in life. Because almost everything – all external expectations, all pride, all fear of embarrassment or failure – these things just fall away in the face of death, leaving only what is truly important.
-Steve Jobs
Why does fear motivate humanity to continue to make the wrong choices? Is there such a thing as wrong choices when every choice is part of the experience? If we live a life of experiences, should we be concerned with the important things in life? After all meaning is meaningless.
Please provide evidence from your observations, studies, and/or readings.